MARCH8 antibody (Middle Region)
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- Target See all MARCH8 Antibodies
- MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MARCH8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CPETSKKNIF EKSPLTEPNF ENKHGYGICH SDTNSSCCTE PEDTGAEIIH
- Predicted Reactivity
- Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against MARCH8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MARCH8
- Top Product
- Discover our top product MARCH8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 291 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))
- Alternative Name
- MARCH8 (MARCH8 Products)
- Synonyms
- MARCH-VIII antibody, MIR antibody, RNF178 antibody, c-MIR antibody, zgc:171495 antibody, 1300017E09Rik antibody, Mir antibody, Mar-08 antibody, MARCH8 antibody, membrane associated ring-CH-type finger 8 antibody, membrane-associated ring finger (C3HC4) 8 antibody, membrane associated ring-CH-type finger 8 L homeolog antibody, MARCH8 antibody, march8 antibody, March8 antibody, march8.L antibody
- Background
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MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. M
Alias Symbols: MARCH-VIII, MIR, RNF178, c-MIR
Protein Interaction Partner: TNFRSF10A, UBC, UBE2H, UBE2D1, TFRC, UBE2D3, IL1RAP, IL1R1, CD86,
Protein Size: 291 - Molecular Weight
- 33 kDa
- Gene ID
- 220972
- NCBI Accession
- NM_001002265, NP_001002265
- UniProt
- Q5T0T0
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