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gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (N-Term) antibody Primary Antibody

GABRB1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776114
$389.00
Plus shipping costs $45.00
100 μL
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  • Target
    gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1)
    Binding Specificity
    • 20
    • 12
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 53
    • 42
    • 39
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)
    Host
    • 47
    • 19
    • 1
    Rabbit
    Clonality
    • 49
    • 18
    Polyclonal
    Conjugate
    • 39
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 47
    • 27
    • 17
    • 13
    • 13
    • 13
    • 12
    • 11
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TLDNRVADQL WVPDTYFLND KKSFVHGVTV KNRMIRLHPD GTVLYGLRIT
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GABRB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GABRB1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 474 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1)
    Alternative Name
    GABRB1 (GABRB1 Antibody Abstract)
    Synonyms
    AW061132, B230208N19Rik, Gabrb-1, GARB1, si:dkey-20i10.4, gamma-aminobutyric acid type A receptor beta1 subunit, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, gamma-aminobutyric acid type A receptor beta 1 subunit, gamma-aminobutyric acid (GABA) A receptor, beta 1, GABRB1, Gabrb1, gabrb1
    Background
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: HSPA8, NEUROD4, NOD1, UBC, CUL1, UBQLN1, ARFGEF2, AKAP5, C1QBP, PIK3CA,
    Protein Size: 474
    Molecular Weight
    51 kDa
    Gene ID
    2560
    NCBI Accession
    NM_000812, NP_000803
    UniProt
    P18505
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