SCN8A antibody (Middle Region)

Catalog No. ABIN2776199

This Rabbit Polyclonal antibody specifically detects SCN8A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Horse and Guinea Pig.

Quick Overview for SCN8A antibody (Middle Region) (ABIN2776199)

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCN8A Antibody

Binding Specificity: Middle Region

Sequence: ESDPEGSKDK LDDTSSSEGS TIDIKPEVEE VPVEQPEEYL DPDACFTEGC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SCN8A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SCN8A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1980 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Alternative Name: SCN8A

Background: Voltage-dependent sodium channels, such as SCN8A, are responsible for the initial membrane depolarization that occurs during generation of action potentials in most electrically excitable cells.
Alias Symbols: CerIII, MED, NaCh6, Nav1.6, PN4, CIAT, CERIII
Protein Interaction Partner: NEDD4, MAPK14, FGF13, GNAO1,
Protein Size: 1980

Molecular Weight: 225 kDa

Gene ID: 6334

NCBI Accession: NM_014191, NP_055006

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound