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SCN8A antibody (C-Term)

SCN8A Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776200
  • Target See all SCN8A Antibodies
    SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
    Binding Specificity
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 25
    • 12
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig
    Host
    • 29
    • 5
    Rabbit
    Clonality
    • 29
    • 5
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN8A antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KSSIFSFRGP GRFRDPGSEN EFADDEHSTV EESEGRRDSL FIPIRARERR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SCN8A. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A
    Top Product
    Discover our top product SCN8A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
    Alternative Name
    SCN8A (SCN8A Products)
    Synonyms
    CERIII antibody, CIAT antibody, EIEE13 antibody, MED antibody, NaCh6 antibody, Nav1.6 antibody, PN4 antibody, AI853486 antibody, C630029C19Rik antibody, dmu antibody, med antibody, mnd-2 antibody, mnd2 antibody, nmf2 antibody, nmf335 antibody, nmf58 antibody, nur14 antibody, seal antibody, sodium voltage-gated channel alpha subunit 8 antibody, sodium channel, voltage-gated, type VIII, alpha antibody, SCN8A antibody, Scn8a antibody
    Background
    This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
    Alias Symbols: MED, PN4, CIAT, NaCh6, CERIII, EIEE13, Nav1.6
    Protein Size: 475
    Molecular Weight
    52 kDa
    Gene ID
    6334
    NCBI Accession
    NM_001177984, NP_001171455
    UniProt
    Q9UQD0
    Pathways
    Sensory Perception of Sound
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