GRIK2 antibody (C-Term)

Catalog No. ABIN2776247

The Rabbit Polyclonal anti-GRIK2 antibody (ABIN2776247) specifically detects GRIK2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for GRIK2 antibody (C-Term) (ABIN2776247)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRIK2 Antibody

Binding Specificity: C-Term

Purpose: GRIK2 Antibody - C-terminal region

Sequence: TANLAAFLTV ERMESPIDSA DDLAKQTKIE YGAVEDGATM TFFKKSKIST

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GRIK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GRIK2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101595

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GRIK2

Background:

Background Information: This gene, GRIK2, encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.

Gene Name: Glutamate receptor, ionotropic, kainate 2

Alternative Symbols: EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2

Protein Name: Glutamate receptor, ionotropic kainate 2

Molecular Weight: 98kDa

Gene ID: 2898

NCBI Accession: NP_786944

UniProt: Q96KS6

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity