KCNMB3 antibody (Middle Region)
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- Target See all KCNMB3 Antibodies
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNMB3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SLTLLGGALI VGMVRLTQHL SLLCEKYSTV VRDEVGGKVP YIEQHQFKLC
- Predicted Reactivity
- Dog: 91%, Human: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against KCNMB3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KCNMB3
- Top Product
- Discover our top product KCNMB3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 277 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
- Alternative Name
- KCNMB3 (KCNMB3 Products)
- Synonyms
- KCNMB3 antibody, BKBETA3 antibody, HBETA3 antibody, KCNMB2 antibody, KCNMBL antibody, SLOBETA3 antibody, EG435726 antibody, Gm5707 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 3 antibody, potassium channel subfamily M regulatory beta subunit 3 S homeolog antibody, potassium large conductance calcium-activated channel, subfamily M beta member 3 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 3 antibody, KCNMB3 antibody, kcnmb3.S antibody, Kcnmb3 antibody
- Background
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KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.
Alias Symbols: KCNMB2, KCNMBL, HBETA3, BKBETA3, SLOBETA3
Protein Size: 277 - Molecular Weight
- 31 kDa
- Gene ID
- 27094
- NCBI Accession
- NM_171828, NP_741979
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