Insulin Receptor antibody (Middle Region)
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- Target See all Insulin Receptor (INSR) Antibodies
- Insulin Receptor (INSR)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Insulin Receptor antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EEVSGTKGRQ ERNDIALKTN GDQASCENEL LKFSFIRTSF DKILLRWEPY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Insr. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product INSR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Insulin Receptor (INSR)
- Alternative Name
- Insr (INSR Products)
- Synonyms
- CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
- Background
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This receptor binds insulin and has a tyrosine-protein kinase activity. When it is present in a hybrid receptor with IGF1R, binds IGF1.
Alias Symbols: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B
Protein Interaction Partner: Arrb2, Src, Akt1, Jup, Irs1, Grb10, Snx9, Dok3, Sh2b2, Flot1, Dok1, Cav3, Socs1, Socs3, Sorbs1, Cav1, Pik3r1,
Protein Size: 1372 - Molecular Weight
- 155 kDa
- Gene ID
- 16337
- NCBI Accession
- NM_010568, NP_034698
- UniProt
- P15208
- Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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