AFT1 antibody (N-Term)
AFT1
Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
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Target
See all AFT1 Antibodies
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AFT1
(Activating Transcription Factor 1 (AFT1))
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Binding Specificity
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N-Term
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Reactivity
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Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig
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Host
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Rabbit
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Clonality
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Polyclonal
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Conjugate
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This AFT1 antibody is un-conjugated
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Application
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Western Blotting (WB)
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Sequence
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DLSSEDTRGR KGDGENSGVS AAVTSMSVPT PIYQTSSGQY IAIAPNGALQ
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Predicted Reactivity
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Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
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Characteristics
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This is a rabbit polyclonal antibody against ATF1. It was validated on Western Blot.
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Purification
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Affinity Purified
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Immunogen
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The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF1
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Top Product
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Discover our top product AFT1 Primary Antibody
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Restrictions
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For Research Use only
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Format
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Liquid
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Concentration
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1 mg/mL
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Buffer
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Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
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Sodium azide
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Precaution of Use
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This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
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Avoid repeat freeze-thaw cycles.
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Storage
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-20 °C
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Storage Comment
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For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Target
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AFT1
(Activating Transcription Factor 1 (AFT1))
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Alternative Name
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ATF1 (AFT1 Products)
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Synonyms
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ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
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Background
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ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Alias Symbols: EWS-ATF1, FUS/ATF-1, TREB36
Protein Interaction Partner: UBC, SRA1, FOSL2, GABPB1, GABPA, EDF1, HNF1B, RPS6KA5, CAMK1, RPS6KA4, CAMK2G, PRKACA, CREBBP, SPI1, JUN, CREM, CREB1, ATF1, CSNK2A2, CSNK2A1, BRCA1, CSNK2B, CAMK2A, FOSL1,
Protein Size: 271
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Molecular Weight
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29 kDa
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Gene ID
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466
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NCBI Accession
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NM_005171, NP_005162
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UniProt
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P18846
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Pathways
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Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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