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PDK2 antibody (Middle Region)

PDK2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777433
  • Target See all PDK2 Antibodies
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Binding Specificity
    • 14
    • 10
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 78
    • 45
    • 40
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Zebrafish (Danio rerio)
    Host
    • 72
    • 9
    Rabbit
    Clonality
    • 66
    • 15
    Polyclonal
    Conjugate
    • 39
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDK2 antibody is un-conjugated
    Application
    • 65
    • 36
    • 36
    • 15
    • 12
    • 12
    • 10
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ELFKNAMRAT VESHESSLIL PPIKVMVALG EEDLSIKMSD RGGGVPLRKI
    Predicted Reactivity
    Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against PDK2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PDK2
    Top Product
    Discover our top product PDK2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 407 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Alternative Name
    PDK2 (PDK2 Products)
    Background
    PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    Alias Symbols: PDHK2
    Protein Interaction Partner: VSIG4, DLAT, ISOC2, HIC2, SGK1, PDK2, PDK1, PDHA1, PDHX, AKT1, HTT,
    Protein Size: 407
    Molecular Weight
    44 kDa
    Gene ID
    5164
    NCBI Accession
    NM_002611, NP_002602
    UniProt
    Q15119
    Pathways
    PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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