KCNA5 antibody (N-Term)
-
- Target See all KCNA5 Antibodies
- KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This KCNA5 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- DPGVRPLPPL PEELPRPRRP PPEDEEEEGD PGLGTVEDQA LGTASLHHQR
- Predicted Reactivity
- Human: 100%, Mouse: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against KCNA5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5
- Top Product
- Discover our top product KCNA5 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 613 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))
- Alternative Name
- KCNA5 (KCNA5 Products)
- Synonyms
- KCNA5 antibody, kcna5 antibody, ATFB7 antibody, HCK1 antibody, HK2 antibody, HPCN1 antibody, KV1.5 antibody, PCN1 antibody, Kv1.5 antibody, Kv1 antibody, potassium voltage-gated channel subfamily A member 5 antibody, potassium channel, voltage gated shaker related subfamily A, member 5 antibody, potassium voltage-gated channel, shaker-related subfamily, member 5 antibody, KCNA5 antibody, kcna5 antibody, Kcna5 antibody
- Background
-
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.
Alias Symbols: ATFB7, HCK1, HK2, HPCN1, KV1.5, MGC117058, MGC117059, PCN1
Protein Interaction Partner: SIRT1, KCNAB2, ERBB2IP, SNTA1, HSP90AA1, TNK2, Rab11a, DCTN2, GNB2L1, KCNAB1, TFRC, SRC, PRKCQ, PRKCB, KCNA5, KCNA4, KCNA3, KCNA2, FYN, FHL1, DYNC1I1, CAV1, ACTN2, UBE2I, SUMO3, RAB5A, RAB4A, DLG4, DLG1, PTPRE,
Protein Size: 613 - Molecular Weight
- 67 kDa
- Gene ID
- 3741
- NCBI Accession
- NM_002234, NP_002225
- UniProt
- P22460
-