SMARCB1 antibody (N-Term)
-
- Target See all SMARCB1 Antibodies
- SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SMARCB1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- RGSLYKRYPS LWRRLATVEE RKKIVASSHG KKTKPNTKDH GYTTLATSVT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SMARCB1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1
- Top Product
- Discover our top product SMARCB1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 385 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
- Alternative Name
- SMARCB1 (SMARCB1 Products)
- Synonyms
- SMARCB1 antibody, BAF47 antibody, INI1 antibody, MRD15 antibody, RDT antibody, RTPS1 antibody, SNF5 antibody, SNF5L1 antibody, Sfh1p antibody, Snr1 antibody, hSNFS antibody, AU020204 antibody, Baf47 antibody, Ini1 antibody, SNF5/INI1 antibody, Snf5 antibody, fc51b01 antibody, smarcb1 antibody, wu:fc51b01 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b antibody, SMARCB1 antibody, Smarcb1 antibody, smarcb1.S antibody, smarcb1b antibody
- Background
-
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.
Alias Symbols: RDT, INI1, SNF5, Snr1, BAF47, RTPS1, Sfh1p, hSNFS, SNF5L1
Protein Interaction Partner: UBC, SOX2, tat, EPAS1, TRA2A, NCSTN, SAP18, EIF4A3, ARID1A, DPF1, VTN, TOP2B, SON, SMARCE1, SMARCD3, SMARCD2, SMARCD1, SMARCC2, SMARCA4, SMARCA2, SMARCC1, ARID1B, HDAC2, APP, PHF10, UBD, COPS5, CUL3, TFAP4, CAND1, RB1CC1, UBB, CEBPB, UL114, UL44, CHFR, DP
Protein Size: 385 - Molecular Weight
- 44 kDa
- Gene ID
- 6598
- NCBI Accession
- NM_003073, NP_003064
- UniProt
- Q12824
-