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TNFSF15 antibody (C-Term)
TNFSF15
Reactivity: Human, Mouse, Cow
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFSF15 Antibody
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Target
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TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Binding Specificity
All epitopes for TNFSF15 antibodies
C-Term
Reactivity
All reactivities for TNFSF15 antibodies
Human, Mouse, Cow
Host
All hosts for TNFSF15 antibodies
Rabbit
Clonality
All clonalities for TNFSF15 antibodies
Polyclonal
Conjugate
All conjugates for TNFSF15 antibodies
This TNFSF15 antibody is un-conjugated
Application
All applications for TNFSF15 antibodies
Western Blotting (WB)
Sequence
CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP
Predicted Reactivity
Cow: 79%, Human: 100%, Mouse: 100%
Characteristics
This is a rabbit polyclonal antibody against TNFSF15. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human TNFSF15
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Discover our top product TNFSF15 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for TNFSF15
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Target
TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Alternative Name
TNFSF15 (TNFSF15 Products )
Synonyms
TTPAL antibody, TL1 antibody, TL1A antibody, VEGI antibody, VEGI192A antibody, Tl1 antibody, Tl1a antibody, Vegi antibody, tumor necrosis factor superfamily member 15 antibody, TNF superfamily member 15 antibody, tumor necrosis factor (ligand) superfamily, member 15 antibody, TNFSF15 antibody, Tnfsf15 antibody
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. Protein Interaction Partner: TNFRSF25, TNFRSF6B, Protein Size: 192
Molecular Weight
21 kDa
Gene ID
9966
Pathways
Positive Regulation of Endopeptidase Activity , Autophagy
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