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PTGES2 antibody (Middle Region)
PTGES2
Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PTGES2 Antibody
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Target
See all PTGES2 Antibodies
PTGES2
(Prostaglandin E Synthase 2 (PTGES2))
Binding Specificity
All epitopes for PTGES2 antibodies
Middle Region
Reactivity
All reactivities for PTGES2 antibodies
Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse
Host
All hosts for PTGES2 antibodies
Rabbit
Clonality
All clonalities for PTGES2 antibodies
Polyclonal
Conjugate
All conjugates for PTGES2 antibodies
This PTGES2 antibody is un-conjugated
Application
All applications for PTGES2 antibodies
Western Blotting (WB)
Sequence
GAAAMYLISK RLKSRHHLQD DVRVDLYEAA NKWVTAVGKD RPFMGGQKPN
Predicted Reactivity
Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 79%, Mouse: 100%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against Ptges2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Mouse Ptges2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PTGES2
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Target
PTGES2
(Prostaglandin E Synthase 2 (PTGES2))
Alternative Name
Ptges2 (PTGES2 Products )
Synonyms
C9orf15 antibody, GBF-1 antibody, GBF1 antibody, PGES2 antibody, mPGES-2 antibody, Pges antibody, 2410099E23Rik antibody, D2Ertd369e antibody, mPGES antibody, mPGES-1 antibody, PTGES2 antibody, ptges2 antibody, zgc:56527 antibody, gbf1 antibody, pges2 antibody, 0610038H10Rik antibody, C79137 antibody, Gbf1 antibody, Mpges2 antibody, Pges2 antibody, MPGES-2 antibody, prostaglandin E synthase 2 antibody, prostaglandin E synthase antibody, prostaglandin E synthase 2-like antibody, PTGES2 antibody, Ptges antibody, Ptges2 antibody, ptgesl antibody, CpipJ_CPIJ003988 antibody, CpipJ_CPIJ018524 antibody, ptges2 antibody
Background
The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta. Alias Symbols: 0610038H10Rik, C79137, Gbf1, Mpges2, Pges2 Protein Size: 384
Molecular Weight
43 kDa
Gene ID
96979
NCBI Accession
NM_133783 , NP_598544
UniProt
Q8BWM0
Pathways
Interferon-gamma Pathway , Cell RedoxHomeostasis , SARS-CoV-2 Protein Interactome
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