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PRDM12 antibody (C-Term)

PRDM12 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781154
  • Target See all PRDM12 Antibodies
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Binding Specificity
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 22
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Pig
    Host
    • 20
    • 2
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRDM12 antibody is un-conjugated
    Application
    • 15
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    NHVRLHTGER PYKCQVCQSA YSQLAGLRAH QKSARHRPPS TALQAHSPAL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
    Top Product
    Discover our top product PRDM12 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 367 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Alternative Name
    PRDM12 (PRDM12 Products)
    Synonyms
    PRDM12 antibody, prdm12 antibody, MGC146714 antibody, PFM9 antibody, pfm9 antibody, Gm998 antibody, PR/SET domain 12 antibody, PR domain containing 12 antibody, PR domain containing 12 L homeolog antibody, PR domain containing 12a antibody, PRDM12 antibody, prdm12 antibody, prdm12.L antibody, Prdm12 antibody, prdm12a antibody
    Background
    PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
    Alias Symbols: PFM9
    Protein Size: 367
    Molecular Weight
    40 kDa
    Gene ID
    59335
    NCBI Accession
    NM_021619, NP_067632
    UniProt
    Q9H4Q4
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