ABCC1 antibody (Middle Region)
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- Target See all ABCC1 Antibodies
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABCC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LFISFLSIFL FMCNHVSALA SNYWLSLWTD DPIVNGTQEH TKVRLSVYGA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against ABCC1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ABCC1
- Top Product
- Discover our top product ABCC1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1531 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
- Alternative Name
- ABCC1 (ABCC1 Products)
- Synonyms
- ABC29 antibody, ABCC antibody, GS-X antibody, MRP antibody, MRP1 antibody, Abcc1a antibody, Abcc1b antibody, Mdrap antibody, Mrp1 antibody, Avcc1a antibody, Mrp antibody, ABCC13 antibody, ATP binding cassette subfamily C member 1 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 1 antibody, multidrug resistance-associated protein 1 antibody, ABCC1 antibody, Abcc1 antibody, LOC100152428 antibody, LOC100346553 antibody
- Background
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ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Alias Symbols: ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
Protein Interaction Partner: UBC, ABCC1, CAV1, TRAF3, NPM1, AZGP1, STT3B, RAVER1, MCU, MRPL17, TMCO1, ATP6V1H, TMX2, TMOD2, NDUFAF3, FKBP8, PUF60, PGRMC2, FLOT1, PDCD6IP, ATP6V1F, EIF3C, PDHX, VDAC3, SURF1, STX4, SAFB, RPS7, NDUFB9, DBT, TMEM173, UNC93B1,
Protein Size: 1531 - Molecular Weight
- 171 kDa
- Gene ID
- 4363
- NCBI Accession
- NM_004996, NP_004987
- UniProt
- P33527
- Pathways
- SARS-CoV-2 Protein Interactome
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