PTPRE antibody (Middle Region)
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- Target See all PTPRE Antibodies
- PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPRE antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VILSMKRGQE YTDYINASFI DGYRQKDYFI ATQGPLAHTV EDFWRMIWEW
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PTPRE. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PTPRE
- Top Product
- Discover our top product PTPRE Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 700 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
- Alternative Name
- PTPRE (PTPRE Products)
- Synonyms
- ptpra antibody, HPTPE antibody, PTPE antibody, R-PTP-EPSILON antibody, PTPe antibody, PTPepsilon antibody, RPTPepsilon antibody, protein tyrosine phosphatase, receptor type E L homeolog antibody, protein tyrosine phosphatase, receptor type E antibody, protein tyrosine phosphatase, receptor type, E antibody, ptpre.L antibody, PTPRE antibody, Ptpre antibody
- Background
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PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Alias Symbols: DKFZp313F1310, HPTPE, PTPE, R-PTP-EPSILON
Protein Interaction Partner: UBC, MAPK3, MAPK1, KCNB1, KCNA5, PTPRD, PTPRS, PTPRE, SRC, YES1, FYN, GRB2,
Protein Size: 700 - Molecular Weight
- 81 kDa
- Gene ID
- 5791
- NCBI Accession
- NM_006504, NP_006495
- UniProt
- P23469
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