CDH23 antibody (N-Term)

Catalog No. ABIN2783851

Product Details anti-CDH23 Antibody

Target: CDH23 (Cadherin 23 (CDH23))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH23 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DHQGVITRKV NIQVGDVNDN APTFHNQPYS VRIPENTPVG TPIFIVNATD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CDH23. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDH23

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Alternative Name: CDH23 (CDH23 Products)

Synonyms: 4930542A03Rik antibody, USH1D antibody, ahl antibody, ahl1 antibody, bob antibody, bus antibody, mdfw antibody, nmf112 antibody, nmf181 antibody, nmf252 antibody, sals antibody, v antibody, CDHR23 antibody, W antibody, cadherin 23 (otocadherin) antibody, cadherin related 23 antibody, cadherin-related 23 antibody, Cdh23 antibody, CDH23 antibody

Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Alias Symbols: CDHR23, USH1D
Protein Interaction Partner: LYN, Dlg4, USH1C, MYO7A,
Protein Size: 406

Molecular Weight: 44 kDa

Gene ID: 64072

NCBI Accession: NM_001171932, NP_001165403

UniProt: A5D6V9

Pathways: Sensory Perception of Sound