PPP2R5E antibody (N-Term)

Catalog No. ABIN2786846

Product Details anti-PPP2R5E Antibody

Target: PPP2R5E (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5E antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QFRSQGKPIE LTPLPLLKDV PSSEQPELFL KKLQQCCVIF DFMDTLSDLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP2R5E. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R5E

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 467 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R5E

Target: PPP2R5E (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E))

Alternative Name: PPP2R5E (PPP2R5E Products)

Synonyms: 4633401M22Rik antibody, AI449017 antibody, B56beta antibody, wdb2 antibody, ppp2r5e antibody, ppp2r5e1 antibody, PPP2R5E antibody, ppp2r5e2 antibody, wdb1 antibody, zgc:85613 antibody, protein phosphatase 2 regulatory subunit B'epsilon antibody, protein phosphatase 2, regulatory subunit B', epsilon antibody, protein phosphatase 2 regulatory subunit B', epsilon antibody, protein phosphatase 2, regulatory subunit B', epsilon isoform b antibody, protein phosphatase 2 regulatory subunit B', beta antibody, protein phosphatase 2, regulatory subunit B', epsilon isoform a antibody, PPP2R5E antibody, Ppp2r5e antibody, ppp2r5eb antibody, ppp2r5e antibody, ppp2r5b.L antibody, ppp2r5e.S antibody, ppp2r5ea antibody

Background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.
Alias Symbols: -
Protein Interaction Partner: PPP2R1A, UBC, TRMT10A, TERF2IP, SAE1, TPD52L2, AARS, EGFR, vpu, SMAD9, CBX5, APP, NOD2, HHV8GK18_gp81, ELAVL1, CHEK2, PIM1, Soga1, Sgol2, PPP2R1B, PPP2CB, PPP2CA, SGOL1, BHLHB9,
Protein Size: 467

Molecular Weight: 55 kDa

Gene ID: 5529

NCBI Accession: NM_006246, NP_006237

UniProt: Q16537

Pathways: PI3K-Akt Signaling