Nodal antibody (Middle Region)

Catalog No. ABIN2787062

Product Details anti-Nodal Antibody

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nodal antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EFHPTNHAYI QSLLKRYQPH RVPSTCCAPV KTKPLSMLYV DNGRVLLDHH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against NODAL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NODAL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nodal

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Alternative Name: NODAL (NODAL Products)

Synonyms: NODAL antibody, Tg.413d antibody, HTX5 antibody, nodal4 antibody, nodal4-A antibody, nr4 antibody, xnr4 antibody, Xnr-1 antibody, nodal antibody, nr1 antibody, nr1-A antibody, nodal growth differentiation factor antibody, nodal homolog (mouse) antibody, nodal antibody, nodal growth differentiation factor L homeolog antibody, nodal homolog 1 L homeolog antibody, Nodal antibody, NODAL antibody, nodal.L antibody, nodal1.L antibody

Background: The protein encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development.
Alias Symbols: MGC138230, HTX5
Protein Size: 347

Molecular Weight: 37 kDa

Gene ID: 4838

NCBI Accession: NM_018055, NP_060525

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity