DBP antibody (Middle Region)

Catalog No. ABIN2787482

Product Details anti-DBP Antibody

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VRRASGCLIT LDQHNGKKSQ AVESANTAHN GKVNGLCFTS DGLHLLTVGT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against DBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DBP

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Alternative Name: DBP (DBP Products)

Synonyms: DBP antibody, DABP antibody, Gc antibody, dbp antibody, tef antibody, D-box binding PAR bZIP transcription factor antibody, D site albumin promoter binding protein antibody, GC, vitamin D binding protein antibody, D site of albumin promoter (albumin D-box) binding protein L homeolog antibody, DBP antibody, Dbp antibody, GC antibody, dbp.L antibody

Background: DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It is transcriptional activator that recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. The protein is not essential for circadian rhythm generation, but modulates important clock output genes.DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family (Khatib et al., 1994 [PubMed 7835883]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 DT217864.1 56-106 52-1518 BC011965.1 1-1467 1519-1658 CA425431.1 1-140 c
Alias Symbols: DABP
Protein Interaction Partner: BATF2, BATF3, BATF, EPAS1, DDIT3, CEBPG, CEBPA, ATF3, HLF, EP300, TEF,
Protein Size: 325

Molecular Weight: 34 kDa

Gene ID: 1628

NCBI Accession: NM_001352, NP_001343

UniProt: Q10586