LKB1 antibody (C-Term)
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- Target See all LKB1 (STK11) Antibodies
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Horse, Guinea Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LKB1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EAPVPIPPSP DTKDRWRSMT VVPYLEDLHG ADEDEDLFDI EDDIIYTQDF
- Predicted Reactivity
- Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against STK11. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human STK11
- Top Product
- Discover our top product STK11 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 433 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- Alternative Name
- STK11 (STK11 Products)
- Synonyms
- pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody
- Background
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STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Alias Symbols: LKB1, PJS, hLKB1
Protein Interaction Partner: SPDEF, SIRT1, PRKAA1, ETV4, CDC37, HSP90AA1, TP63, Eif2b1, Ap2m1, SNRK, APP, TNIP2, SIK1, STRADA, STUB1, UBE2D2, MARK2, GSK3B, STRADB, CAB39, KIF23, USP11, SMARCC1, SMARCA4, LIMS1, HSPA1A, FKBP5, RPAP3, MARK4, UBC, CAB39L, WDR48, RPS6KB1, MOB4, MARK1, RPS
Protein Size: 433 - Molecular Weight
- 49 kDa
- Gene ID
- 6794
- NCBI Accession
- NM_000455, NP_000446
- UniProt
- Q15831
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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