PCSK2 antibody (Middle Region)
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- Target See all PCSK2 Antibodies
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCSK2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LASTFSNGRK RNPEAGVATT DLYGNCTLRH SGTSAAAPEA AGVFALALEA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PCSK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PCSK2
- Top Product
- Discover our top product PCSK2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 638 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Alternative Name
- PCSK2 (PCSK2 Products)
- Synonyms
- NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody
- Background
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This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: NEC2, PC2, SPC2, NEC 2, NEC-2
Protein Interaction Partner: PMCH, SCG5, IAPP, THRA,
Protein Size: 638 - Molecular Weight
- 58 kDa
- Gene ID
- 5126
- NCBI Accession
- NM_002594, NP_002585
- UniProt
- Q5REC2
- Pathways
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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