Rho-related GTP-binding protein antibody (C-Term)
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- Target See all Rho-related GTP-binding protein (RhO (pan)) Antibodies
- Rho-related GTP-binding protein (RhO (pan))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Rho-related GTP-binding protein antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE
- Predicted Reactivity
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 93%
- Characteristics
- This is a rabbit polyclonal antibody against RHO. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RHO
- Top Product
- Discover our top product RhO (pan) Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 348 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Rho-related GTP-binding protein (RhO (pan))
- Alternative Name
- RHO (RhO (pan) Products)
- Target Type
- Chemical
- Background
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Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Alias Symbols: CSNBAD1, MGC138309, MGC138311, OPN2, RP4
Protein Interaction Partner: DERL1, EDEM1, VCP, UBC, HSPA4, DNAJB2, RHO, PPP2CA, GRK5, GRK6, ARR3, GNGT1, SAG, GRK1, PRKCA, ADRBK1,
Protein Size: 348 - Molecular Weight
- 39 kDa
- Gene ID
- 6010
- NCBI Accession
- NM_000539, NP_000530
- UniProt
- P08100
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