RFC2 antibody (Middle Region)
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- Target See all RFC2 Antibodies
- RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RFC2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IQSRCAVLRY TKLTDAQILT RLMNVIEKER VPYTDDGLEA IIFTAQGDMR
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against RFC2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RFC2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 320 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))
- Alternative Name
- RFC2 (RFC2 Products)
- Synonyms
- 2610008M13Rik antibody, 40kDa antibody, AI326953 antibody, Recc2 antibody, RFC40 antibody, replication factor C subunit 2 antibody, replication factor C (activator 1) 2 antibody, LOC100231971 antibody, RFC2 antibody, Rfc2 antibody
- Background
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The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome.
Alias Symbols: A1, MGC3665, RFC40
Protein Interaction Partner: CEP76, SUMO2, PCNA, UBC, RPA3, RPA2, RPA1, C14orf166, RTCB, LRRFIP1, PRKDC, KRT18, FLII, DDX1, RFC4, PRKAR1A, PAXIP1, MDC1, TP53BP1, ECT2, BRCA1, BARD1, CHTF18, RFC5, RFC3, RFC1, PURA, NEDD8, RAD18, CAND1, COPS5, CUL3, SMARCAD1, MYC, tat, DDX11, CHD1L, PM
Protein Size: 320 - Molecular Weight
- 35 kDa
- Gene ID
- 5982
- NCBI Accession
- NM_002914, NP_002905
- UniProt
- Q75MT5
- Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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