PPP2R4 antibody (N-Term)

Catalog No. ABIN2789005

Product Details anti-PPP2R4 Antibody

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WKRSQAYADY IGFILTLNEG VKGKKLTFEY RVSEMWNEVH EEKEQAAKQS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP2R4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 358 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Alternative Name: PPP2R4 (PPP2R4 Products)

Synonyms: PP2A antibody, PR53 antibody, PTPA antibody, 2610042B21Rik antibody, C77440 antibody, N28142 antibody, PTPRA antibody, Ppp2r4 antibody, fc23d07 antibody, ppp2r4 antibody, wu:fc23d07 antibody, zgc:92766 antibody, pp2a antibody, ppp2r4.L antibody, pr53 antibody, ptpa antibody, protein phosphatase 2 phosphatase activator antibody, protein phosphatase 2 protein activator antibody, protein phosphatase 2 phosphatase activator L homeolog antibody, PTPA antibody, Ptpa antibody, ptpa antibody, ptpa.L antibody

Background: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family.
Alias Symbols: MGC2184, PP2A, PR53, PTPA
Protein Interaction Partner: AMOT, MID1, BHLHB9, SP3, STAT1, IER3, UBC, PRKCB, MAPT, EIF4EBP1, RACGAP1, APP, CAV1, AKT1, MAP2K3, MARK2, ATM, STK26, AURKB, CYLD, PPP1CA, HHV8GK18_gp81, SP1, PPP2CA, MDM2, SET, ARRB2, PIM1, PTEN, PPP2R1A, MYOCD, MYLPF, CCT5, CCT8, CCT2, CCT4, CCT7, CCT3
Protein Size: 358

Molecular Weight: 39 kDa

Gene ID: 5524

NCBI Accession: NM_178001, NP_821068

UniProt: Q15257

Pathways: PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades