GCKR antibody (Middle Region)

Catalog No. ABIN2789593

The Rabbit Polyclonal anti-GCKR antibody is suitable to detect GCKR in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for GCKR antibody (Middle Region) (ABIN2789593)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCKR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GCKR Antibody

Binding Specificity: Middle Region

Purpose: Gckr Antibody - middle region

Sequence: FLPVLVGFNP VSMARNDPIE DWRSTFRQVA ERMQKMQEKQ EAFVLNPAIG

Predicted Reactivity: Cow: 82%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against Gckr. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Gckr

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63698-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Alternative Name: Gckr

Background:

Background Information: Gckr inhibits glucokinase by forming an inactive complex with this enzyme.

Gene Name: glucokinase (hexokinase 4) regulator

Alternative Symbols: GK, GKRP

Protein Name: Glucokinase regulatory protein

Molecular Weight: 65kDa

Gene ID: 231103

NCBI Accession: NP_659158

UniProt: Q91X44

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus