BCMA antibody (C-Term)

Catalog No. ABIN2789670

Product Details anti-BCMA Antibody

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCMA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYTVEECTCE DCIKSKPKVD SDHCFPLPAM EEGATILVTT KTNDYCKSLP

Predicted Reactivity: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TNFRSF17. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 184 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCMA

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Alternative Name: TNFRSF17 (TNFRSF17 Products)

Synonyms: TNFRSF17 antibody, BCM antibody, BCMA antibody, CD269 antibody, TNFRSF13A antibody, Tnfrsf13 antibody, Tnfrsf13a antibody, TNF receptor superfamily member 17 antibody, tumor necrosis factor receptor superfamily, member 17 antibody, Tnfrsf17 antibody, TNFRSF17 antibody

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Alias Symbols: BCM, BCMA, CD269
Protein Interaction Partner: TRAF6, TRAF5, UBC, TNFSF13, TNFSF13B, TRAF3, TRAF2, TRAF1,
Protein Size: 184

Molecular Weight: 20 kDa

Gene ID: 608

NCBI Accession: NM_001192, NP_001183

UniProt: Q02223