FCAR antibody (C-Term)

Catalog No. ABIN2789926

Product Details anti-FCAR Antibody

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FDRFSLAKEG ELSLPQHQSG EHPANFSLGP VDLNVSGIYR LHPPRLHDAE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FCAR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 209 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: FCAR (FCAR Products)

Synonyms: CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody

Background: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CD89
Protein Interaction Partner: FCGR1A, CD79A, PPP2CA, OSCAR, PILRA, LYN, FCAR,
Protein Size: 209

Molecular Weight: 23 kDa

Gene ID: 2204

NCBI Accession: NM_133274, NP_579808

UniProt: Q92588