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PHAX antibody (Middle Region)
PHAX
Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PHAX Antibody
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Target
See all PHAX Antibodies
PHAX
(phosphorylated Adaptor For RNA Export (PHAX))
Binding Specificity
All epitopes for PHAX antibodies
Middle Region
Reactivity
All reactivities for PHAX antibodies
Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Pig
Host
All hosts for PHAX antibodies
Rabbit
Clonality
All clonalities for PHAX antibodies
Polyclonal
Conjugate
All conjugates for PHAX antibodies
This PHAX antibody is un-conjugated
Application
All applications for PHAX antibodies
Western Blotting (WB)
Sequence
NYLLAKKLRK ESQEHTKDLD KELDEYMHGG KKMGSKEEEN GQGHLKRKRP
Predicted Reactivity
Cow: 92%, Dog: 92%, Guinea Pig: 75%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 83%, Rabbit: 79%, Rat: 77%
Characteristics
This is a rabbit polyclonal antibody against PHAX. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PHAX
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PHAX
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Target
PHAX
(phosphorylated Adaptor For RNA Export (PHAX))
Alternative Name
PHAX (PHAX Products )
Synonyms
RNUXA antibody, 2810055C14Rik antibody, 4933427L19Rik antibody, AU018701 antibody, AU018854 antibody, D18Ertd65e antibody, Rnuxa antibody, p55 antibody, phosphorylated adaptor for RNA export antibody, PHAX antibody, Phax antibody
Background
PHAX is a phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. PHAX is also a bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Alias Symbols: RNUXA Protein Interaction Partner: CIAO1, UBC, LIN28B, LIN28A, ZNF346, HSP90B1, CALD1, SNORD13P1, SNORD118, LOC366310, PAXIP1, EIF4B, CAND1, CUL3, SUMO2, ZWINT, GADD45G, TNFSF11, MKNK1, VAV1, STK3, RPS6KA1, RAD23A, PDPK1, GRB7, UBXN2A, ASPSCR1, NSFL1C, XPO1, SNORD3A, Protein Size: 394
Molecular Weight
44 kDa
Gene ID
51808
NCBI Accession
NM_032177 , NP_115553
UniProt
Q9H814
Pathways
Ribonucleoprotein Complex Subunit Organization
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