SREBF2 antibody (Middle Region)
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- Target See all SREBF2 Antibodies
- SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Dog, Cow, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SREBF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PASDSGSQAG FSPYSIDSEP GSPLLDDAKV KDEPDSPPVA LGMVDRSRIL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SREBF2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SREBF2
- Top Product
- Discover our top product SREBF2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1141 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
- Alternative Name
- SREBF2 (SREBF2 Products)
- Synonyms
- SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody
- Background
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SREBF2 is a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SREBP2, bHLHd2
Protein Interaction Partner: UBC, ERLIN2, MRPS6, NAE1, MAPK3, MAPK1, PARK7, SCAP, SREBF2, SREBF1, NPAT, HINFP, TRRAP, SUMO2, RNF139, SMAD3, HNF4A, ATF6, KLF13, LZTR1, ABLIM2, ATF7IP, ZDHHC17, COPS5, OS9, PIAS3, CASP8AP2, ARHGEF1, PIAS2, SLC4A4, PIAS1, ZYX, ZMYM2, UBE2I, TTC1, SPTBN1,
Protein Size: 1141 - Molecular Weight
- 124 kDa
- Gene ID
- 6721
- NCBI Accession
- NM_004599, NP_004590
- UniProt
- Q12772
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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