HTR2A antibody (N-Term)
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- Target See all HTR2A Antibodies
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HTR2A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN
- Predicted Reactivity
- Human: 100%, Mouse: 78%, Pig: 92%
- Characteristics
- This is a rabbit polyclonal antibody against HTR2A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A
- Top Product
- Discover our top product HTR2A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 471 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
- Alternative Name
- HTR2A (HTR2A Products)
- Synonyms
- 5-HT2A antibody, HTR2 antibody, 5-HT-2 antibody, 5-HT-2A antibody, 5-HTR2A antibody, LOC100009461 antibody, E030013E04 antibody, Htr-2 antibody, Htr2 antibody, 5Ht-2 antibody, 5HT2A antibody, 5HTR2A antibody, HTR2A antibody, Htr2a antibody, 5HT2 antibody, 5-hydroxytryptamine receptor 2A antibody, 5-hydroxytryptamine (serotonin) receptor 2A antibody, HTR2A antibody, Htr2a antibody
- Background
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HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: LYN, CBL, NDUFB10, ANKS1B, MRPL28, EIF3F, DLG4, PON2, NME3, GNAQ, PPP5C, MAP1A, RPS6KA3, NTRK3, JAK2, GNA11, GNAI1, GLUL,
Protein Size: 471 - Molecular Weight
- 52 kDa
- Gene ID
- 3356
- NCBI Accession
- NM_000621, NP_000612
- UniProt
- P28223
- Pathways
- JAK-STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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