HTR2A antibody (N-Term)

Catalog No. ABIN2792273

This anti-HTR2A antibody is a Rabbit Polyclonal antibody detecting HTR2A in WB. Suitable for Human, Mouse and Pig.

Quick Overview for HTR2A antibody (N-Term) (ABIN2792273)

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reactivity: Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HTR2A Antibody

Binding Specificity: N-Term

Sequence: DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN

Predicted Reactivity: Human: 100%, Mouse: 78%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against HTR2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR2A

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Alternative Name: HTR2A

Background: HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: LYN, CBL, NDUFB10, ANKS1B, MRPL28, EIF3F, DLG4, PON2, NME3, GNAQ, PPP5C, MAP1A, RPS6KA3, NTRK3, JAK2, GNA11, GNAI1, GLUL,
Protein Size: 471

Molecular Weight: 52 kDa

Gene ID: 3356

NCBI Accession: NM_000621, NP_000612

UniProt: P28223

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process