HTR2A antibody (N-Term)

Catalog No. ABIN2792273

The Rabbit Polyclonal anti-HTR2A antibody (ABIN2792273) specifically detects HTR2A in WB. The antibody is reactive with Human, Mouse and Pig samples.

Quick Overview for HTR2A antibody (N-Term) (ABIN2792273)

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reactivity: Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HTR2A Antibody

Binding Specificity: N-Term

Purpose: HTR2A Antibody - N-terminal region

Sequence: DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN

Predicted Reactivity: Human: 100%, Mouse: 78%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against HTR2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR2A

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Alternative Name: HTR2A

Background:

Background Information: HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Alternative Symbols: HTR2, 5-HT2A

Protein Name: 5-hydroxytryptamine receptor 2A

Molecular Weight: 53 kDa

Gene ID: 3356

NCBI Accession: NP_000612

UniProt: P28223

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process