PAX2A antibody (Middle Region)
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- Target See all PAX2A Antibodies
- PAX2A (Paired Box Gene 2a (PAX2A))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Rabbit, Sheep, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAX2A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DPVGSYSING ILGIPRSNGE KRKRDEDVSE GSVPNGDSQS GVDSLRKHLR
- Cross-Reactivity
- Human
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PAX2
- Top Product
- Discover our top product PAX2A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 417 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAX2A (Paired Box Gene 2a (PAX2A))
- Alternative Name
- PAX2 (PAX2A Products)
- Synonyms
- PAPRS antibody, Opdc antibody, Pax-2 antibody, Pax-2a antibody, XPax-2 antibody, XPax2 antibody, pax-2 antibody, pax2 antibody, xPax-2a antibody, PAXZF-B antibody, cb378 antibody, noi antibody, pax-b antibody, pax2.1 antibody, pax2a1 antibody, pax[zf-b] antibody, paxb antibody, pax2.2 antibody, paired box 2 antibody, paired box 2 L homeolog antibody, paired box 2a antibody, paired box 2b antibody, PAX2 antibody, Pax2 antibody, pax2.L antibody, pax2a antibody, pax2b antibody
- Background
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PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: RP11-179B2.1
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
Protein Size: 417 - Molecular Weight
- 45 kDa
- Gene ID
- 5076
- NCBI Accession
- NM_000278, NP_000269
- UniProt
- Q02962
- Pathways
- Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation
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