EIF3L antibody (N-Term)

Catalog No. ABIN2795880

Product Details anti-EIF3L Antibody

Target: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Binding Specificity: AA 12-40, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3L antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Mouse EIF3L (N-term) Antibody

Immunogen: This EIF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human EIF3L.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000EIF3L Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.320 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for EIF3L

Target: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Alternative Name: EIF3L (EIF3L Products)

Synonyms: wu:fb66c05 antibody, zgc:64147 antibody, EIF3EIP antibody, EIF3S11 antibody, EIF3S6IP antibody, HSPC021 antibody, HSPC025 antibody, MSTP005 antibody, 0610011H21Rik antibody, D15N1e antibody, Eif3eip antibody, Eif3ip antibody, Eif3s6ip antibody, HSP-66Y antibody, PAF67 antibody, eif3eip antibody, eif3s6ip antibody, eukaryotic translation initiation factor 3, subunit 6 interacting protein antibody, eukaryotic translation initiation factor 3 subunit L antibody, eukaryotic translation initiation factor 3, subunit L antibody, eukaryotic translation initiation factor 3 subunit L L homeolog antibody, eif3s6ip antibody, EIF3L antibody, Eif3l antibody, eif3l.L antibody

Background:

Target Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Gene Symbol: EIF3L

Molecular Weight: 66727 Da

Gene ID: 51386

UniProt: Q9Y262

Pathways: Ribonucleoprotein Complex Subunit Organization