ARHGEF11 antibody (Center)
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- Target See all ARHGEF11 Antibodies
- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
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Binding Specificity
- AA 605-632, Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARHGEF11 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human ARHGEF11 (Center) Antibody
- Immunogen
- This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ARHGEF11 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000ARHGEF11 Antibody (Center) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
- Alternative Name
- ARHGEF11 (ARHGEF11 Products)
- Synonyms
- ARHGEF11 antibody, GTRAP48 antibody, PDZ-RHOGEF antibody, B930073M02 antibody, E130307F09 antibody, PDZ-RhoGEF antibody, Prg antibody, RhoGEF antibody, mKIAA0380 antibody, Gtrap48 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, rho guanine nucleotide exchange factor 11 antibody, arhgef11 antibody, ARHGEF11 antibody, Arhgef11 antibody, LOC511220 antibody
- Background
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Target Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Gene Symbol: ARHGEF11
- Molecular Weight
- 167704 Da
- Gene ID
- 9826
- UniProt
- O15085
- Pathways
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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