ESX Homeobox 1 antibody (N-Term)

Catalog No. ABIN2799370

Product Details anti-ESX Homeobox 1 Antibody

Target: ESX Homeobox 1 (ESX1)

Binding Specificity: AA 28-55, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESX Homeobox 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human ESX1 (N-term) Antibody

Immunogen: This ESX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human ESX1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000ESX1 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.280 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ESX Homeobox 1

Target: ESX Homeobox 1 (ESX1)

Alternative Name: ESX1 (ESX1 Products)

Synonyms: ESX1L antibody, ESXR1 antibody, Spx1 antibody, ESX homeobox 1 antibody, extraembryonic, spermatogenesis, homeobox 1 antibody, ESX1 antibody, Esx1 antibody

Background:

Target Description: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.

Gene Symbol: ESX1

Molecular Weight: 44297 Da

Gene ID: 80712

UniProt: Q8N693