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ARNTL antibody (AA 151-250) (AbBy Fluor® 594)

ARNTL Reactivity: Human, Rat, Mouse WB, FACS, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN2810351
  • Target See all ARNTL Antibodies
    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
    Binding Specificity
    • 15
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivity
    • 57
    • 44
    • 42
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 53
    • 7
    • 1
    Rabbit
    Clonality
    • 48
    • 13
    Polyclonal
    Conjugate
    • 30
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARNTL antibody is conjugated to AbBy Fluor® 594
    Application
    • 43
    • 15
    • 15
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BMAL1
    Isotype
    IgG
    Top Product
    Discover our top product ARNTL Primary Antibody
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
    Alternative Name
    BMAL1 (ARNTL Products)
    Synonyms
    BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody
    Background

    Synonyms: ARNT like protein 1 brain and muscle, ARNTL, Aryl hydrocarbon receptor nuclear translocator like, Aryl hydrocarbon receptor nuclear translocator like protein 1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic helix loop helix PAS orphan MOP3, bHLH PAS protein JAP3, bHLHe5, BMAL 1, BMAL1c, Brain and muscle ARNT like 1, cycle, JAP 3, JAP3, Member of PAS protein 3, Member of PAS superfamily 3, MOP3, PAS domain-containing protein 3, PASD 3, PASD3, TIC.

    Background: Component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with CLOCK is required for E-box-dependent transactivation, for CLOCK nuclear translocation and degradation, and, for phosphorylation of both CLOCK and ARNTL. Interaction with PER and CRY proteins requires translocation to the nucleus. Interaction of the CLOCK-ARNTL heterodimer with PER or CRY inhibits transcription activation. Interacts with HSP90, with AHR in vitro, but not in vivo.

    Gene ID
    406
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
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