Progesterone Receptor antibody (AA 349-377)

Catalog No. ABIN2843803

Product Details anti-Progesterone Receptor Antibody

Target: Progesterone Receptor (PGR)

Binding Specificity: AA 349-377

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This PGR/PR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from human PGR/PR.

Clone: 312CT8-2-1-6

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PGR/PR Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR (PGR Products)

Synonyms: NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

Molecular Weight: 98981

Gene ID: 5241

NCBI Accession: NP_000917, NP_001189403, NP_001258091

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration