AP2B1 antibody (Internal Region)
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- Target See all AP2B1 Antibodies
- AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AP2B1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Cow (Bovine)
- Cross-Reactivity (Details)
- Bovine (100 %)
- Characteristics
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Rabbit polyclonal antibody to beta-Adaptin (adaptor-related protein complex 1, beta 1 subunit)
beta-Adaptin antibody [N3C1], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human beta-Adaptin. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product AP2B1 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.55 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
- Alternative Name
- beta-Adaptin (AP2B1 Products)
- Synonyms
- 5-HT(2B) antibody, 5-HT2B antibody, ADTB2 antibody, AP105B antibody, AP2-BETA antibody, CLAPB1 antibody, 1300012O03Rik antibody, AI788979 antibody, fa16e07 antibody, wu:fa16c06 antibody, wu:fa16e07 antibody, wu:fc18c08 antibody, zgc:55659 antibody, 5-hydroxytryptamine receptor 2B antibody, adaptor related protein complex 2 beta 1 subunit antibody, adaptor-related protein complex 2, beta 1 subunit antibody, adaptor related protein complex 2 beta 1 subunit L homeolog antibody, HTR2B antibody, AP2B1 antibody, Ap2b1 antibody, ap2b1 antibody, ap2b1.L antibody
- Background
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Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist.
Cellular Localization: Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle membrane - Molecular Weight
- 105 kDa
- Gene ID
- 162
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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