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CDC42BPA antibody

CDC42BPA Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855436
  • Target See all CDC42BPA Antibodies
    CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
    Reactivity
    • 21
    • 12
    • 11
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 17
    • 3
    • 1
    Rabbit
    Clonality
    • 18
    • 3
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC42BPA antibody is un-conjugated
    Application
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to MRCK alpha (CDC42 binding protein kinase alpha (DMPK-like))
    MRCK alpha antibody
    Purification
    Affinity purified by Protein A.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human MRCK alpha. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: U87-MG

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
    Alternative Name
    CDC42 binding protein kinase alpha (CDC42BPA Products)
    Synonyms
    MRCK antibody, MRCKA antibody, PK428 antibody, Mrck antibody, Pk428 antibody, A930014J19Rik antibody, DMPK-like antibody, CDC42BPA antibody, CDC42 binding protein kinase alpha antibody, GDNF family receptor alpha 2 antibody, serine/threonine-protein kinase MRCK alpha antibody, CDC42 binding protein kinase alpha (DMPK-like) antibody, CDC42BPA antibody, Cdc42bpa antibody, GFRA2 antibody, LOC100182779 antibody, LOC100545977 antibody
    Background
    The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

    Cellular Localization: Cytoplasm (By similarity)
    Molecular Weight
    197 kDa
    Gene ID
    8476
    UniProt
    Q5VT25
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