CYP3A4 antibody (Internal Region)
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- Target See all CYP3A4 Antibodies
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP3A4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Human (100 %)
- Characteristics
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Rabbit Polyclonal antibody to CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4)
CYP3A4 antibody [N2C2], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CYP3A4. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CYP3A4 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: *Rat liver microsome
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.03 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Alternative Name
- CYP3A4 (CYP3A4 Products)
- Synonyms
- CP33 antibody, CP34 antibody, CYP3A antibody, CYP3A3 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, HLP antibody, NF-25 antibody, P450C3 antibody, P450PCN1 antibody, MGC108372 antibody, CYP3A80 antibody, CYP3A4 antibody, CYP3A21 antibody, CYPIIIA21 antibody, CYP3A12 antibody, cytochrome P450 family 3 subfamily A member 4 antibody, cytochrome P450 family 3 subfamily A member 43 antibody, cytochrome P450 3A4 antibody, cytochrome P450, subfamily IIIA, polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, cytochrome P450, family 3, subfamily A, polypeptide 4 antibody, CYP3A4 antibody, CYP3A43 antibody, PTRG_01782 antibody, PTRG_06060 antibody, cyp3a4 antibody
- Background
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Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.
Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane - Molecular Weight
- 57 kDa
- Gene ID
- 1576
- Pathways
- Steroid Hormone Biosynthesis
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