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PDGFRB antibody
PDGFRB
Reactivity: Mammalian
WB, ELISA
Host: Sheep
Polyclonal
unconjugated
Product Details anti-PDGFRB Antibody
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Target
See all PDGFRB Antibodies
PDGFRB
(Platelet Derived Growth Factor Receptor beta (PDGFRB))
Reactivity
All reactivities for PDGFRB antibodies
Mammalian
Host
All hosts for PDGFRB antibodies
Sheep
Clonality
All clonalities for PDGFRB antibodies
Polyclonal
Conjugate
All conjugates for PDGFRB antibodies
This PDGFRB antibody is un-conjugated
Application
All applications for PDGFRB antibodies
Western Blotting (WB), ELISA
Specificity
This antibody reacts with bovine albumin by immunoelectrophoresis and ELISA,and may also cross-react with albumin from other species.1 ml@ 1 mg/ml
Purification
Protein G affinity chromatography
Immunogen
PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen.
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Alternatives
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Application Details
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Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by protein G chromatography and supplied in PBS with 0.05 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target Details for PDGFRB
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Target
PDGFRB
(Platelet Derived Growth Factor Receptor beta (PDGFRB))
Alternative Name
PDGFr (PDGFRB Products )
Synonyms
AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody
Background
Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Inositol Metabolic Process , Glycosaminoglycan Metabolic Process , Smooth Muscle Cell Migration , Platelet-derived growth Factor Receptor Signaling
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