Botulinum Neurotoxin Type A antibody (Light Chain)

Catalog No. ABIN2859515

Product Details anti-Botulinum Neurotoxin Type A Antibody

Target: Botulinum Neurotoxin Type A

Binding Specificity: Light Chain

Reactivity: Clostridium botulinum

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Botulinum Neurotoxin Type A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein G Sepharose Chromatography

Immunogen: Type A Neurotoxin light chain

Application Details

Application Notes: Suitable for use in dot blot, ELISA and Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.6 mg/mL (OD280nm , E0.1% = 1.4)

Buffer: 1xPBS, pH 7.2 containing 20 % Glycerol, None, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Botulinum Neurotoxin Type A

Target: Botulinum Neurotoxin Type A

Abstract: Botulinum Neurotoxin Type A Products

Synonyms: bna antibody, botA antibody, botulinum neurotoxin type A antibody, atx antibody

Background: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A

Gene ID: 1491

UniProt: P10845