Vitronectin antibody (AA 121-133)
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- Target See all Vitronectin (VTN) Antibodies
- Vitronectin (VTN)
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Binding Specificity
- AA 121-133
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Vitronectin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). This antibody is human-specific (no reactivity with cat, dog, cow, sheep, goat, pig, rabbit, horse). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133. Reactivity: Can be used to purify vitronectin from human plasma by affinity chromatography. It can also be used to quantitatively affinity-deplete human plasma or serum of vitronectin. It partially denatures vitronectin upon antibody binding. It binds equally well to native and denatured vitronectin and can be used to quantitative vitronectin in human plasma in a sandwich ELISA with clone 6F211. It does not interfere with the binding of any known vitronectin ligands. Also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well.
- Purification
- Protein A/G purified
- Immunogen
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Human vitronectin purified from plasma by heparin-affinity chromatography.
Type of Immunogen: Purified protein - Clone
- HV2
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product VTN Primary Antibody
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- Application Notes
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Approved: ELISA (1:32000), WB (1:100)
Usage: Suitable for use in ELISA, Western Blot. ELISA: 1:32000. Western Blot: 1:100. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.2, 15 mM sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- Vitronectin (VTN)
- Alternative Name
- VTN / Vitronectin (VTN Products)
- Synonyms
- VTN antibody, DKFZp470F0511 antibody, LOC100228142 antibody, vtn antibody, zgc:112277 antibody, V75 antibody, VN antibody, VNT antibody, AI256434 antibody, Vn antibody, Aa1018 antibody, vitronectin antibody, vitronectin a antibody, vitronectin b antibody, vitronectin L homeolog antibody, VTN antibody, vtn antibody, vtna antibody, vtnb antibody, CpipJ_CPIJ016691 antibody, vtn.L antibody, Vtn antibody
- Background
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Name/Gene ID: VTN
Family: Matrix Protein
Synonyms: VTN, Epibolin, Serum-spreading factor, VNT, S-protein, Somatomedin B, V75, VN, Complement S-protein, Serum spreading factor, Vitronectin - Gene ID
- 7448
- UniProt
- P04004
- Pathways
- Autophagy, Smooth Muscle Cell Migration
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