APOC3 antibody

Catalog No. ABIN289326

Product Details anti-APOC3 Antibody

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Affinity chromatography purified

Immunogen: ApoC-III antibody was raised in goat using produced from apolipoprotein type C-III derived from human plasma as the immunogen.

Application Details

Application Notes: ELISA: 1:5,000-1:10,000, IHC: 1:50-1:200, IP: 1:100, WB: 1:5,000-1:10,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: 0.125 M Na5 5 7, pH 8.0, with 0.075 NaCl, 0.005 EDTA, and 0.01 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: ApoC-III (APOC3 Products)

Synonyms: APOC3 antibody, APOCIII antibody, HALP2 antibody, Apoc antibody, ApoC-III antibody, apo-CIII antibody, Apo-CIII antibody, apolipoprotein C3 antibody, apolipoprotein C-III antibody, APOC3 antibody, Apoc3 antibody

Background: Apolipoprotein C-III is a very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to inhibit hepatic uptake of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Pathways: Carbohydrate Homeostasis, Lipid Metabolism