CREM antibody (AA 336-349)

Catalog No. ABIN294682

Product Details anti-CREM Antibody

Target: CREM (CAMP Responsive Element Modulator (CREM))

Binding Specificity: AA 336-349

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CREM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human CREM. This antibody is expected to recognise the following protein isoforms of human CREM protein: a (NP_853549.1), e (NP_874387.1), f (NP_874388.1), k (NP_874393.1), l (NP_874394.1), m (NP_877570.1), n (NP_877571.1), o (NP_877572.1), p (NP_877573.1), q (NP_878270.1), v (NP_898883.1). This antibody is not expected to cross-react with CREB protein.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human (100%), Gibbon (93%), Monkey (93%), Mouse (93%), Rat (93%), Goat (93%), Elephant (93%), Dog (93%), Bat (93%), Bovine (93%), Horse (93%), Opossum (93%), Marmoset (86%), Platypus (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide LETLKDICSPKTDY from the C-terminus of human CREM (NP_853549.1, NP_874387.1, NP_874388.1, NP_874393.1, NP_874394.1, NP_877570.1, NP_877571.1, NP_877572.1, NP_877573.1, NP_878270.1, NP_898883.1). Percent identity with other species by BLAST analysis: Human (100%), Gibbon (93%), Monkey (93%), Mouse (93%), Rat (93%), Goat (93%), Elephant (93%), Dog (93%), Bat (93%), Bovine (93%), Horse (93%), Opossum (93%), Marmoset (86%), Platypus (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000), WB (1:16000, 1 - 3 μg/mL)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Alternative Name: CREM / ICER (CREM Products)

Synonyms: CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody

Background: Name/Gene ID: CREM

Synonyms: CREM, CREM-2, CREM 2alpha-b protein, CREM 2beta-a protein, HCREM-2, Inducible cAMP early repressor, ICER

Gene ID: 1390

NCBI Accession: NP_853549, NP_874387, NP_874388, NP_874393, NP_874394, NP_877570, NP_877571, NP_877572, NP_877573, NP_878270, NP_898883

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway