Factor XII Light Chain antibody
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
C6B7
unconjugated
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- Target
- Factor XII Light Chain
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
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Application
- ELISA
- Specificity
- Reacts with human Factor XII Light Chain and inhibits 50 % of Factor XII activity at 100 nM. Suitable for coagulation assays.
- Purification
- Purified (protein G)
- Immunogen
- Purified human Factor XII.
- Clone
- C6B7
- Isotype
- IgG1
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-
- Application Notes
- Working dilution: Optimal dilution should be determined by the end user.
- Restrictions
- For Research Use only
-
- Buffer
- PBS, pH 7.4.
- Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Factor XII Light Chain
- Background
-
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. This single chain zymogen circulates in blood andis converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain wich contains only a catalytic domain.
Coagulation factor XII (EC:3.4.21.38) Hageman factor, HAF Coagulation factor XIIa light chain Beta-factor XIIa part 2 HAE3 HAEX Gene name : F12 - Gene ID
- 2161
- UniProt
- P00748
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