TACR3 antibody
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- Target See all TACR3 Antibodies
- TACR3 (Tachykinin Receptor 3 (TACR3))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TACR3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Recognizes human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kD multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory. AHP1492 does not recognize NK1R or NK2R.
- Purification
- Affinity purified
- Immunogen
- An 18 amino acid peptide from near the center of human TACR3.
- Top Product
- Discover our top product TACR3 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (5 μg/mL), WB (0.5 - 1 μg/mL)
Usage: Western Blot: LS-C56946 detects a band of approximately 46kD in RAW264.7 cell lysates. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Target
- TACR3 (Tachykinin Receptor 3 (TACR3))
- Alternative Name
- TACR3 / NK3R (TACR3 Products)
- Synonyms
- HH11 antibody, NK-3R antibody, NK3R antibody, NKR antibody, TAC3RL antibody, Nk3r antibody, Nkr antibody, Tac3r antibody, Nmkr antibody, tachykinin receptor 3 antibody, neuromedin-K receptor antibody, TACR3 antibody, LOC100544805 antibody, Tacr3 antibody
- Background
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Name/Gene ID: TACR3
Subfamily: Tachykinin
Family: GPCR
Synonyms: TACR3, HH11, Nmk-r, NK3R, NKR, Tachykinin receptor 3, Neurokinin B, Neurokinin B receptor, NK-3 receptor, NK-3R, TAC3R, Neurokinin 3 receptor, Neurokinin beta receptor, Neuromedin-K receptor, TAC3RL - Gene ID
- 6870
- UniProt
- P29371
- Pathways
- Feeding Behaviour
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