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ACVR1C/ALK7 antibody (AA 22-113)

ACVR1C Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021054
  • Target See all ACVR1C/ALK7 (ACVR1C) Antibodies
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Binding Specificity
    • 16
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-113
    Reactivity
    • 45
    • 43
    • 29
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 54
    • 5
    Rabbit
    Clonality
    • 56
    • 3
    Polyclonal
    Conjugate
    • 29
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVR1C/ALK7 antibody is un-conjugated
    Application
    • 51
    • 25
    • 20
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LSPGLKCVCL LCDSSNFTCQ TEGACWASVM LTNGKEQVIK SCVSLPELNA QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP ME
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2).
    Isotype
    IgG
    Top Product
    Discover our top product ACVR1C Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Alternative Name
    ACVR1C (ACVR1C Products)
    Synonyms
    ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
    Background
    ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008],ACVR1C,ACVRLK7,ALK7,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Growth factor,ACVR1C
    Molecular Weight
    37 kDa/46 kDa/49 kDa/54 kDa
    Gene ID
    130399
    UniProt
    Q8NER5
    Pathways
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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