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PSMD4/ASF antibody (AA 1-377)
Psmd4
Reactivity: Human
WB, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PSMD4/ASF Antibody
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Target
See all PSMD4/ASF (Psmd4) Antibodies
PSMD4/ASF (Psmd4)
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
Binding Specificity
All epitopes for PSMD4/ASF antibodies
AA 1-377
Reactivity
All reactivities for PSMD4/ASF antibodies
Human
Host
All hosts for PSMD4/ASF antibodies
Rabbit
Clonality
All clonalities for PSMD4/ASF antibodies
Polyclonal
Conjugate
All conjugates for PSMD4/ASF antibodies
This PSMD4/ASF antibody is un-conjugated
Application
All applications for PSMD4/ASF antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
Sequence
MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA ASAAEAGIAT TGTEDSDDAL LKMTISQQEF GRTGLPDLSS MTEEEQIAYA MQMSLQGAEF GQAESADIDA SSAMDTSEPA KEEDDYDVMQ DPEFLQSVLE NLPGVDPNNE AIRNAMGSLA SQATKDGKKD KKEEDKK
Cross-Reactivity
Human, Monkey, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human PSMD4 (NP_002801.1).
Isotype
IgG
Alternatives
(show)
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) (AA 92-141) antibody
Psmd4
Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Rabbit, Guinea Pig, Horse, Monkey, Pig, Chicken, Xenopus laevis, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) (C-Term) antibody
Psmd4
Reactivity: Human, Rat, Cow, Sheep, Rabbit, Monkey, Pig, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PSMD4/ASF
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Target
PSMD4/ASF (Psmd4)
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
Alternative Name
PSMD4 (Psmd4 Products )
Synonyms
af-1 antibody, mcb1 antibody, pub-r5 antibody, rpn10 antibody, PSMD4 antibody, DDBDRAFT_0202512 antibody, DDBDRAFT_0232981 antibody, DDB_0202512 antibody, DDB_0232981 antibody, AF antibody, AF-1 antibody, ASF antibody, MCB1 antibody, Rpn10 antibody, S5A antibody, pUB-R5 antibody, xrpn10c antibody, Af1 antibody, Mcb1 antibody, angiocidin antibody, im:6912672 antibody, psmd4 antibody, wu:fc68c04 antibody, zgc:110247 antibody, proteasome 26S subunit, non-ATPase 4 antibody, 26S proteasome non-ATPase regulatory subunit 4 antibody, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antibody, proteasome 26S subunit, non-ATPase 4 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antibody, proteasome 26S subunit, non-ATPase 4b antibody, psmd4 antibody, PSMD4 antibody, LOC100194679 antibody, psmD4 antibody, LOC100283637 antibody, Smp_000740.1 antibody, psmd4.L antibody, Psmd4 antibody, psmd4b antibody
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.,PSMD4,AF,AF-1,ASF,MCB1,Rpn10,S5A,pUB-R5,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,PSMD4
Molecular Weight
28 kDa/40 kDa
Gene ID
5710
UniProt
P55036
Pathways
Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Ubiquitin Proteasome Pathway
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